Archive for the 'Endometrial Cancer' Category

Disease of Women! Yes this Endometrial cancer is primarily a disease of postmenopausal women. The average age at diagnosis is approximately 60 years.

Women diagnosed with endometrial cancer when they are younger than 40 years make up only 5% of the total cases.

Specific risk factors such as morbid obesity, chronic anovulation, and hereditary syndromes affect these women invariably. This type of disease is more common in white women when compared to black women

The most common symptom is PMP bleeding. Women with PMP vaginal bleeding having a gynecologic malignancy are only 10-20%. 12-16% of women with endometrial cancer are diagnosed with PMP bleeding.

Women are usually older than 40 years with premenopausal bleeding due to endometrial cancer. However, the diagnosis of this cancer needs to be considered in younger women with a history of anovulatory bleeding and obesity.

The differential diagnosis must include breakthrough bleeding with estrogen replacement therapy, atrophic vaginitis, endometrial/cervical polyps, atrophic endometrium and sub mucosal leiomyomas.

As the patient’s age and number of risk factors (Etiology) increase, the etiology of the PMP bleeding is more likely to be endometrial cancer.