The Future In Testing For Identification Of Prostate Cancer Metastasis

metastasisThe new investigation used to track and identify the metastasis in the prostate cancer has a very important role in the early and effective treatment of the persons suffering from this disease.

As the technology is evolving daily into more and more progressive treatment methods the future of the cancer patients seems to look brighter every day.

According to a study recently published by the scientists from the University of Southern California, a new investigation can help in detecting the prostate cancer reappearance even in the situation in which the usual histopathological analysis does not show the regional lymphatic ganglions being invaded by tumor cells.

As doctor Richard Cote, professor of pathology and urology at USC sustains, the test seems to be the most efficient investigation form which can be used to track the recurrence of the prostate cancer.

This investigation can help the search for the unusual metastasis at the lymphatic ganglions level as well as discovering the sign of metastasis in the bone marrow area and presently is operated in the research state for other types of cancer such as lung and breast carcinoma.

Professor Richard Cote together with a very large research team have analyzed 3914 lymph nodes harvested from 180  cancer patients, diagnosed as negative in the malign cells test done through standard examination with the optical microscope.

During this time the nodes in question were also evaluated through the new immuno-histo –chemical method which is able to detect even one single cell of tumoral tissue through positive reaction of the cell in question with the anti cytokeratin and anti PSA (specific prostate antigene).

The team of researchers has found unusual metastasis at the 24 patients from the initial number of 180.

In another stage of action was compared the recurrence of cancer and the survival of the patients with or without unusual metastasis.

The prognosis of the patients tested positive after the new investigation was a bit reserved, they having a similar evolution to the ones testing positive at the post surgery standard histopathological analysis.

In conclusion, the team of the researchers from USC has demonstrated the importance of the accurate detection of the unusual lymphatic metastasis, they being the most effective means of tracking the recurrence of the prostate cancer.

Their identification is essential in the post surgery therapeutical treatment especially in the case of the systemic helping therapy necessary in all the cases of tumor dissemination but can also be useless and ineffective for a patient without metastasis.


Posted in: Prostate Cancer

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